Genes and mutations associated with autoimmune diseases
If you tested your DNA with a personal genomics service like 23andMe, DeCODEme, FTDNA's Family Finder or another testing company, you can learn more about your risk factors for hundreds of diseases. Many of these SNP's are tested but not (yet) part of the report provided by personal genomics companies. This is free extra information.
We recommend that you install the SNPTips add-on for Mozilla Firefox to browse these pages. It allows you to upload your DNA results in the browser and show instantly which allele variant you have for each of the SNP listed below.
List of auto-immune diseases with the associated genes
Risk alleles : Substantially lower risk
(over 3x less), moderately lower risk (up
to 3x less), normal, slightly higher
risk (up to 3x more), greatly increased risk
(over 3x more). Normal alleles marked
with a * mean that the person is a carrier of the disease. Depending on
the testing company, sometimes A is reported as T, and G is reported as
C, or vice-versa. Question marks (?) mean that we doubt the validity of
the risk alleles because they are too common.
Testing companies :
A = 23andMe (all versions) ; A2* = 23andMe (v2 only) ; A2 = 23andMe (v2 & v3) ; A3 = 23andMe (v3 only)
B = DeCODEme Bold letters indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme.