I'm HV. My maternal line is from the Tosco-Emilian Appenines, on the emilian side (Modena). That area was historically inhabited by ligurians, etruscans, gauls, romans. What population could have most likely contributed to my family line? Or can it be even older - paleolithic maybe?
MtDNA is even more difficult to link to specific ancient populations than is yDNA. One coding region difference mutation can separate two clusters of a specific mtDNA clade of a haplogroup by thousands of years and who knows what migration groups.
For example, my closest mtDNA match is an American of British Isles ancestry. We are both within a specific branch of U2e. Yet, after having our complete FGS mtDNA results analyzed, we discovered that our most recent common maternal line ancestress likely lived around 1500 to 1000 years ago. It could even stretch to 2000 years ago, or longer.
Specifically as to HV and the Etruscans, yes, HV has been found in ancient Etruscan samples, but it also has a strong presence in parts of Italy, like Sicily and Calabria, which were never settled by the Etruscans. It could very likely just be Neolithic in Italy in most cases, but it could have been carried by other peoples as well.
If we ever got some complete mtDNA analysis of Etruscan remains, (none of the studies that have been done so far are of any worth whatsoever, in my opinion, as they are usually only HVRI sequences, and they are in addition badly done and analyzed ) or of other ancient remains in Italy, and if someone had a complete FGS done, then some logical conclusions might be drawn, but not until then.
