Genetic study Human genetic structure in Northwest France provides new insights into West European historical demography

[Tautalus]

Abstract

The demographical history of France remains largely understudied despite its central role toward understanding modern population structure across Western Europe. Here, by exploring publicly available Europe-wide genotype datasets together with the genomes of 3234 present-day and six newly sequenced medieval individuals from Northern France, we found extensive fine-scale population structure across Brittany and the downstream Loire basin and increased population differentiation between the northern and southern sides of the river Loire, associated with higher proportions of steppe vs. Neolithic-related ancestry. We also found increased allele sharing between individuals from Western Brittany and those associated with the Bell Beaker complex. Our results emphasise the need for investigating local populations to better understand the distribution of rare (putatively deleterious) variants across space and the importance of common genetic legacy in understanding the sharing of disease-related alleles between Brittany and people from western Britain and Ireland.
​

Human genetic structure in Northwest France provides new insights into West European historical demography - Nature Communications

Here, the authors look at present day and medieval genome samples from Northern France to piece together demographic history and population structure across Brittany and the Loire basin.

www.nature.com

 

[MOESAN]

It's the reviewed work we saw some years ago. Good job.

 

[qh777]

Are there g25 coordinates for the 6 medieval samples?

Relevant video:

 

[Tautalus]

Are there g25 coordinates for the 6 medieval samples?

I don't think so.

France is a gateway between the northern and southern parts of the continent and genetics reflect geography, so it is natural that it is a diverse country with different genetic clusters.
And Brittany has always held a special place in cultural, historical and genetic terms.