kingdavid
Regular Member
- Messages
- 2,377
- Reaction score
- 1,417
- Points
- 113
- Y-DNA haplogroup
- Mizrahi e-FGC7391
The archaeological site of Pompeii is one of the 54 UNESCO World Heritage sites in Italy, thanks to its uniqueness: the town was completely destroyed and buried by a Vesuvius’ eruption in 79 AD. In this work, we present a multidisciplinary approach with bioarchaeological and palaeogenomic analyses of two Pompeian human remains from the Casa del Fabbro. We have been able to characterize the genetic profile of the first Pompeian’ genome, which has strong affinities with the surrounding central Italian population from the Roman Imperial Age. Our findings suggest that, despite the extensive connection between Rome and other Mediterranean populations, a noticeable degree of genetic homogeneity exists in the Italian peninsula at that time. Moreover, palaeopathological analyses identified the presence of spinal tuberculosis and we further investigated the presence of ancient DNA from Mycobacterium tuberculosis. In conclusion, our study demonstrates the power of a combined approach to investigate ancient humans and confirms the possibility to retrieve ancient DNA from Pompeii human remains. Our initial findings provide a foundation to promote an intensive and extensive paleogenetic analysis in order to reconstruct the genetic history of population from Pompeii, a unique archaeological site.
source:
https://www.nature.com/articles/s41598-022-10899-1
p.s
fascinating the male carried y haplogroup A-M13
Sex determination and uniparental genetic markers
The genetic sex determination (estimated by RY parameter26, and by the X chromosome coverage) confirmed the morphological determination that individual A was a male (Table 1).
The mitochondrial DNA haplogroup was identified using HaploGrep227,28 (Table 1), and revealed that the individual belongs to the haplogroup clade HV0a, the main monophyletic branch of HV0 and subclade of haplogroup HV. This mitochondrial lineage is absent among published Roman Imperial individuals from Italy29. In Europe, the first evidence of the HV haplogroup is from a Magdalenian period individual from Spain30 while in Italy from a Mesolithic individual from Sicily (Favignana)31. The HV haplogroup is actually associated with the early human dispersal in Eurasia after the Last Glacial Maximum (LGM)32. It is unevenly spread across Europe with highest frequencies in the Near East (~11%)33, in south Europe (from ~4% to ~11%)34 and in the Balkan peninsula (~8%)35. HV0a coalesces around 12.5–11.0 kya ago34 and, among the extant populations, is common in Sardinia36.
Individual A, albeit at low coverage (Table 1), was found to belong to the Y-chromosome lineage A-M13 (A1b1b2b), a rare lineage absent among ancient individuals from the Italian Peninsula29, mainly found in Eastern Africa (~ 40%), but with known occurrences, at much lower frequencies, in the Near East (Turkey, Yemen, Egypt, Palestine, Jordan, Oman and Saudi Arabia) and the Mediterranean islands of Sardinia, Cyprus and Lesbos37,38,39,40. Downstream of A-M13 and restricting the analysis to transversions polymorphisms, the individual can be placed at A-V5880, a sub-haplogroup that contains all A-M13 positive Sardinians from past studies39,40, and that has been dated to coalesce around 7.62 (± 0.92) thousands of years ago, using Bayesian analysis40.
according to user teenpean47 from anthrogenica
he was here in the A-m13 tree:
Yleaf 3.0:
Code:
A-V6275
Snipsa:
Code:
Result (40.0% 344 -5 +479): A-V3663
thats the european branch that was found in sardinians
https://www.yfull.com/tree/A-V6275*/
source:
https://www.nature.com/articles/s41598-022-10899-1
p.s
fascinating the male carried y haplogroup A-M13
Sex determination and uniparental genetic markers
The genetic sex determination (estimated by RY parameter26, and by the X chromosome coverage) confirmed the morphological determination that individual A was a male (Table 1).
The mitochondrial DNA haplogroup was identified using HaploGrep227,28 (Table 1), and revealed that the individual belongs to the haplogroup clade HV0a, the main monophyletic branch of HV0 and subclade of haplogroup HV. This mitochondrial lineage is absent among published Roman Imperial individuals from Italy29. In Europe, the first evidence of the HV haplogroup is from a Magdalenian period individual from Spain30 while in Italy from a Mesolithic individual from Sicily (Favignana)31. The HV haplogroup is actually associated with the early human dispersal in Eurasia after the Last Glacial Maximum (LGM)32. It is unevenly spread across Europe with highest frequencies in the Near East (~11%)33, in south Europe (from ~4% to ~11%)34 and in the Balkan peninsula (~8%)35. HV0a coalesces around 12.5–11.0 kya ago34 and, among the extant populations, is common in Sardinia36.
Individual A, albeit at low coverage (Table 1), was found to belong to the Y-chromosome lineage A-M13 (A1b1b2b), a rare lineage absent among ancient individuals from the Italian Peninsula29, mainly found in Eastern Africa (~ 40%), but with known occurrences, at much lower frequencies, in the Near East (Turkey, Yemen, Egypt, Palestine, Jordan, Oman and Saudi Arabia) and the Mediterranean islands of Sardinia, Cyprus and Lesbos37,38,39,40. Downstream of A-M13 and restricting the analysis to transversions polymorphisms, the individual can be placed at A-V5880, a sub-haplogroup that contains all A-M13 positive Sardinians from past studies39,40, and that has been dated to coalesce around 7.62 (± 0.92) thousands of years ago, using Bayesian analysis40.
according to user teenpean47 from anthrogenica
he was here in the A-m13 tree:
Yleaf 3.0:
Code:
A-V6275
Snipsa:
Code:
Result (40.0% 344 -5 +479): A-V3663
thats the european branch that was found in sardinians
https://www.yfull.com/tree/A-V6275*/
