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Eupedia Home > Genetics > Genes & SNP's > Mutations related to neuropsychological conditions
Genes and mutations associated with neuropsychological conditions and disorders
If you tested your DNA with a personal genomics service like 23andMe , DeCODEme , FTDNA 's Family Finder or another testing company, you can learn more about your risk factors for hundreds of diseases. Many of these SNP's are tested but not (yet) part of the report provided by personal genomics companies. This is free extra information.
We recommend that you install the SNPTips add-on for Mozilla Firefox to browse these pages. It allows you to upload your DNA results in the browser and show instantly which allele variant you have for each of the SNP listed below.
What can DNA tell you about yourself ?
List of neuropsychological conditions and disorders with associated genes and SNP's
Alleles : This list comprises positive, neutral and negative traits
and conditions. Therefore we won't refer to risk factor like for diseases
here. Correlated alleles can be either strongly
associated (over 3x higher chances) or moderately
associated (up to 3x higher chances) with each condition/trait.
In some cases the allele can be
negatively correlated
(lower chances). Depending on the testing company, sometimes A is reported
as T, and G is reported as C, or vice-versa.
Testing companies :
A = 23andMe (all versions) ; A2* = 23andMe (v2 only) ; A2 = 23andMe (v2 & v3) ; A3 = 23andMe (v3 only)
B = FamilyTreeDNA (FamilyFinder)
Bold letters indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme.
Description
Chromosome
Gene
SNP
Alleles
Tested by*
Links
ADHD
3
SLC9A9
rs1242075
CC , CT ,
TT
A3
Gizer et al. (2009) , Anney et al. (2008) , Faraone at al. (2001) , ADHD Genetic Research
3
HES1
rs4686673
AA , AG ,
GG
A3
4
CLOCK
rs1801260
AA, AG, GG
A
4
DRD5
Dinucleotide repeat
148-bp allele
5
SLC1A3
rs2269272
A3
5
SLC6A3 (DAT1)
rs27072
AA , AG ,
GG
A
6
HTR1B
rs6296
CC, CG , GG
A
7
DDC
rs11575454
CC , CG ,
GG
rs1466163
AA , AG ,
GG
9
DBH
rs1611115
CC, CT, TT
A
11
FADS2
rs518511
AA, AC , CC
11
DRD4
rs1800955
CC, CT , TT
VNTR
7-repeat
11
BDNF
rs6265
AA , AG , GG
A
12
NTF3
rs6332
AA , AG ,
GG
A
12
TPH2
rs1386493
AA , AG ,
GG
A
rs17110747
AA, AG , GG
rs1843809
AA, AC , CC
A
13
HTR2A
rs6314
AA , AG ,
GG
A
16
SLC6A2 (NET)
rs3785143
AA , AG ,
GG
A
17
ARRB2
rs7208257
AA, AG , GG
17
PNMT
rs200173
AA , AG ,
GG
17
5-HTT (SERT)
rs25531
AA, AG , GG ,
A3
20
SNAP25
rs3746544
AA , AC ,
CC
A
rs3787283
A3
rs363026
AA , AC ,
CC
rs6039806
AA, AC , CC ,
A3
22
ADRBK2
rs3730315
AA , AG , GG
Autism
1
PTGS2
rs2745557
AA , AG ,
GG
A3
SNPedia
2
ITGA4
rs1143674
AA , AG ,
GG
A3
Wikipedia
3
HTR3C
rs6766410
AA , AC , CC
A, B
rs6807362
CC , CG, GG
A3
5
5p15
rs10513025
CC , CT , TT
A3
Source
5
DRD1
rs265981
AA, AG , GG
A
rs4532
CC, CT , TT
A
rs686
AA , AG ,
GG
A
7
MET
rs1858830
CC , CG ,
GG
A
7
DOCK4
rs2217262
AA AC , CC
A, B
Source
9
KDM4C
rs722628
A, B
Source
9
MAPKAP1
rs536861
-
Source
11
CD44
rs2421826
CC , CT, TT
A, B
Source
11
LDLRAD3
rs1358054
-
Source
12
PVRIG
rs1445442
A
Source
12
APPL2
rs2272495
CC, CT , TT
A, B
(22q13.3 deletion syndrome)
22
SHANK3
rs397514705
CC, CT , TT
(22q13.3 deletion syndrome)
22
SHANK3
rs9616915
CC , CT, TT
A3
Source
Autism (social communication problem)
14
-
rs2352908
-
Source
Autism (social communication problem)
6
6p22
rs9257616
-
Source
Autism (delayed onset of speech)
7
CNTNAP2
rs7794745
AA, AT , TT
A
rs2710102
CC , CT, TT
A
Autism (Asperger's syndrome)
1
DISC1
rs1322784
A3
5
APC
rs1804197
AA , AC , CC
A
rs2229992
CC, CT, TT
A2*
rs42427
AA, AG, GG
rs459552
AA , AT, TT
A
rs465899
AA, AG, GG
A3
Anxiety
1
NGF
rs6330
A
12
TPH2
rs4570625
GG , GT, TT
A
rs4565946
A
Bipolar
disorder
5
DAT
SNPedia
- Genetic Future
3
-
rs6442925
CC, CT , TT
A, B
Source
4
-
rs534654
CC, CT , TT
A, B
Source
6
FKBP5
rs7757037
AA , AG , GG
A, B
Source
12
CACNA1C
rs1006737
AA , AG , GG
A3
Source
rs2159100
CC, CT , TT
A, B
12
TPH2
rs4570625
GG , GT, TT
A, B
Source
rs11178997
AA , AT, TT
A
rs17110563
CC, CT , TT
A, B
Source
12
CUX2
rs3847953
A
Source
12
FAM109A
rs933399
A, B
Source
13
HTR2A
Genetic Future , Wikipedia
13
DGKH
rs1012053
AA, AC , CC
A
16
PALB2
rs420259
AA , AG, GG
A
22
CSNK1E
rs1534891
CC, CT , TT
A, B
Source
22
BCR
rs140504
AA , AG, GG
A
rs131690
AA, AG , GG
A
rs131702
GG , GT ,
TT
A3
Bipolar disorder (lithium treatment)
3
GADL1
rs17026688
T carriers respond better to lithium
source
rs17026651
Depression
1
MTHFR
rs1801133
AA , AG, GG
A
Kendler et al. (2006) - BJPsych
2
PDE11A
rs3770018
AA, AC , CC
5
DAT
7
CHRM2
rs1824024
AA, AC, CC
A
rs2061174
AA, AG, GG
A
rs324650
AA, AT, TT
A
11
BDNF
rs6265
AA , AG, GG
A
11
TPH1
rs1799913
GG, GT, TT
A
rs7933505
AA , AG, GG
A
13
HTR2A
17
SERT (5HTT)
21
PDE9A
rs729861
CC , CT ,
TT
22
BCR
rs3761418
AA, AG , GG
A3
rs2267012
AA, AG , GG
A3
rs2267013
AA, AG , GG
A
rs2267015
AA , AT ,
TT
rs2156921
AA, AG , GG
A
rs3313172
CC , CG ,
GG
Dyslexia
6
KIAA0319
rs761100
GG , GT, TT
A
SNPedia
rs4504469
CC, CT , TT
A
rs3212236
AA , AG, GG
A
6
DCDC2
rs793862
AA , AG ,
GG
A
rs807701
CC , CT ,
TT
A
6
TTRAP
rs2143340
CC , CT ,
TT
A
Epilepsy
18
ME2
rs642698
AA , AC, CC
A
Obsessive-Compulsive
Disorder
3
DRD3
rs6280
CC, CT , TT
A
Link
11
ANKK1
rs1800497
AA , AG ,
GG
A
12
TPH2
rs4570625
GG , GT, TT
A
rs4565946
CC , CT, TT
A
17
SERT (5HTT)
17
SLC6A4
rs25531
A3
rs25532
CC , CT ,
TT
A3
22
COMT
rs4680
AA , AG ,
GG
A
Spittoon
Schizophrenia
A
DISC1
rs3738401
AA , AG, GG
A
SNPedia
- Hall et al. (2006)
rs6675281
CC, CT, TT
A
A
CHI3L1
rs4950928
CC, CG, GG
A
6
DTNBP1
rs760761
AA , AG, GG
A
rs1018381
AA , AG, GG
A
rs2619522
AA, AC, CC
A
8
SLC18A1
rs2270641
GG , GT, TT
10
intergenic
rs17101921
AA , AG, GG
13
HTR2A
11
DRD2
rs1801028
CC, CG , GG
A
rs6277
CC , CT ,
TT
A
11
TPH1
rs7933505
A
Szgene
rs1800532
AA , AC, CC
A
rs211105
A
11
intergenic
rs10790212
CC, CT, TT
A
11
intergenic
rs497768
A
22
GNB1L
rs2269726
CC, CT , TT
A
22
COMT
rs4680
AA, AG , GG
A
rs737865
AA , AG, GG
A
rs165599
AA , AG, GG
A
X
CSF2RA
rs4129148
CC, CG , GG
A
rs28694718
CC, CT , TT
A
rs28414810
CC, CG, GG
A2*
X
IL3RA
rs6422441
CC , CT, TT
rs6603272
GG , GT, TT
A
rs17883192
CC , CG ,
GG
A
Social
Phobia
A
RGS2
rs4606
CC , CG ,
GG
17
SLC6A4 (SERT or 5HTT)
rs140701
AA , AG ,
GG
A
rs3794808
CC, CT , TT
A
rs4583306
AA, AG , GG
A
rs25531
A3
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